Mechanisms for the temporal regulation of substrate ubiquitination by the anaphase-promoting complex/cyclosome
Abstract The anaphase-promoting complex/cyclosome (APC/C) is a multi-subunit, multifunctional ubiquitin ligase that controls the temporal degradation of numerous cell cycle regulatory proteins to direct the unidirectional cell cycle phases. Several different mechanisms contribute to ensure the corre...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
| Published: |
BMC
2019-12-01
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| Series: | Cell Division |
| Subjects: | |
| Online Access: | https://doi.org/10.1186/s13008-019-0057-5 |