HOTTIP-miR-205-ZEB2 Axis Confers Cisplatin Resistance to Ovarian Cancer Cells

HOTTIP-miR-205-ZEB2 Axis Confers Cisplatin Resistance to Ovarian Cancer Cells

Ovarian cancer is a deadly gynecological malignancy with resistance to cisplatin a major clinical problem. We evaluated a role of long non-coding (lnc) RNA HOTTIP (HOXA transcript at the distal tip) in the cisplatin resistance of ovarian cancer cells, using paired cisplatin sensitive and resistant A...

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Bibliographic Details
Main Authors: Yu-Jie Dong, Wei Feng, Yan Li
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-07-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
ovarian cancer
cisplatin resistance
HOTTIP
miR-205
ZEB2
Online Access:https://www.frontiersin.org/articles/10.3389/fcell.2021.707424/full

Internet

https://www.frontiersin.org/articles/10.3389/fcell.2021.707424/full

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