The antiepileptic effect of Gastrodiae Rhizoma through modulating overexpression of mTOR and attenuating astrogliosis in pilocarpine mice model

The antiepileptic effect of Gastrodiae Rhizoma through modulating overexpression of mTOR and attenuating astrogliosis in pilocarpine mice model

Abstract Objective To investigate the effect of water extract of Gastrodiae Rhizoma (GR) on the development of acquired temporal lobe epilepsy (TLE) and on regulating the expression of the mammalian target of rapamycin (mTOR) and semaphorin 3F (SEMA3F). Methods A pilocarpine‐induced status epileptic...

Full description

Bibliographic Details
Main Authors: Ka Lai Yip, Chi Man Koon, Zi Yi Chen, Ping Chook, Ping Chung Leung, Steven Schachter, Wai Hong Leung, Chung Tong Mok, Howan Leung
Format: Article
Language:English
Published: Wiley 2020-03-01
Series:Epilepsia Open
Subjects:
antiepileptic
astrogliosis
Gastrodiae Rhizoma
mTOR
neuronal atrophy
SEMA3F
Online Access:https://doi.org/10.1002/epi4.12372

Internet

https://doi.org/10.1002/epi4.12372

Similar Items