Clinical Protocol for a Longitudinal Cohort Study Employing Systems Biology to Identify Markers of Vaccine Immunogenicity in Newborn Infants in The Gambia and Papua New Guinea

Clinical Protocol for a Longitudinal Cohort Study Employing Systems Biology to Identify Markers of Vaccine Immunogenicity in Newborn Infants in The Gambia and Papua New Guinea

Background: Infection contributes to significant morbidity and mortality particularly in the very young and in low- and middle-income countries. While vaccines are a highly cost-effective tool against infectious disease little is known regarding the cellular and molecular pathways by which vaccines...

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Main Authors: Olubukola T. Idoko, Kinga K. Smolen, Oghenebrume Wariri, Abdulazeez Imam, Casey P. Shannon, Tida Dibassey, Joann Diray-Arce, Alansana Darboe, Julia Strandmark, Rym Ben-Othman, Oludare A. Odumade, Kerry McEnaney, Nelly Amenyogbe, William S. Pomat, Simon van Haren, Guzmán Sanchez-Schmitz, Ryan R. Brinkman, Hanno Steen, Robert E. W. Hancock, Scott J. Tebbutt, Peter C. Richmond, Anita H. J. van den Biggelaar, Tobias R. Kollmann, Ofer Levy, Al Ozonoff, Beate Kampmann
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-04-01
Series:Frontiers in Pediatrics
Subjects:
markers
newborn
vaccine
immunogenicity
systems biology
OMICS
Online Access:https://www.frontiersin.org/article/10.3389/fped.2020.00197/full

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https://www.frontiersin.org/article/10.3389/fped.2020.00197/full

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