henn-1/HEN1 Promotes Germline Immortality in Caenorhabditis elegans

Summary: The germline contains an immortal cell lineage that ensures the faithful transmission of genetic and, in some instances, epigenetic information from one generation to the next. Here, we show that in Caenorhabditis elegans, the small RNA 3′-2′-O-methyltransferase henn-1/HEN1 is required for...

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Bibliographic Details
Main Authors: Joshua M. Svendsen, Kailee J. Reed, Tarah Vijayasarathy, Brooke E. Montgomery, Rachel M. Tucci, Kristen C. Brown, Taylor N. Marks, Dieu An H. Nguyen, Carolyn M. Phillips, Taiowa A. Montgomery
Format: Article
Language:English
Published: Elsevier 2019-12-01
Series:Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124719314470