Therapeutic Approaches to Treat Mitochondrial Diseases: “One-Size-Fits-All” and “Precision Medicine” Strategies

Therapeutic Approaches to Treat Mitochondrial Diseases: “One-Size-Fits-All” and “Precision Medicine” Strategies

Primary mitochondrial diseases (PMD) refer to a group of severe, often inherited genetic conditions due to mutations in the mitochondrial genome or in the nuclear genes encoding for proteins involved in oxidative phosphorylation (OXPHOS). The mutations hamper the last step of aerobic metabolism, aff...

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Bibliographic Details
Main Authors: Emanuela Bottani, Costanza Lamperti, Alessandro Prigione, Valeria Tiranti, Nicola Persico, Dario Brunetti
Format: Article
Language:English
Published: MDPI AG 2020-11-01
Series:Pharmaceutics
Subjects:
mitochondria
mitochondrial DNA
mitochondrial disorders
pharmacological therapy
gene therapy
precision medicine
Online Access:https://www.mdpi.com/1999-4923/12/11/1083

Internet

https://www.mdpi.com/1999-4923/12/11/1083

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