Hyaluronic acid and platelet-rich plasma, a new therapeutic alternative for scleroderma patients: a prospective open-label study

Abstract Background Systemic sclerosis is a systemic connective tissue disease characterized by endothelium damage, fibrosis, and subsequent atrophy of the skin. Perioral fibrosis produces a characteristic microstomia together with microcheilia, both of which cause severe difficulties and affects pa...

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Bibliographic Details
Main Authors: Roberto Pirrello, Barbara Verro, Giulia Grasso, Piero Ruscitti, Adriana Cordova, Roberto Giacomelli, Francesco Ciccia, Giuliana Guggino
Format: Article
Language:English
Published: BMC 2019-12-01
Series:Arthritis Research & Therapy
Subjects:
Online Access:https://doi.org/10.1186/s13075-019-2062-0