Hyaluronic acid and platelet-rich plasma, a new therapeutic alternative for scleroderma patients: a prospective open-label study
Abstract Background Systemic sclerosis is a systemic connective tissue disease characterized by endothelium damage, fibrosis, and subsequent atrophy of the skin. Perioral fibrosis produces a characteristic microstomia together with microcheilia, both of which cause severe difficulties and affects pa...
Main Authors: | Roberto Pirrello, Barbara Verro, Giulia Grasso, Piero Ruscitti, Adriana Cordova, Roberto Giacomelli, Francesco Ciccia, Giuliana Guggino |
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Format: | Article |
Language: | English |
Published: |
BMC
2019-12-01
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Series: | Arthritis Research & Therapy |
Subjects: | |
Online Access: | https://doi.org/10.1186/s13075-019-2062-0 |
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