Potential Utility of Synthetic D-Lactate Polymers in Skin Cancer

Increased breakdown of glucose through glycolysis in both aerobic and anaerobic conditions is a hallmark feature of mammalian cancer and leads to increased production of L-lactate. The high-level lactate present within the tumor microenvironment is reused as a crucial biofuel to support rapid cancer...

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Bibliographic Details
Main Authors: Anushka Dikshit, Junqi Lu, Amy E. Ford, Simone Degan, Yingai J. Jin, Huiying Sun, Amanda Nichols, April K.S. Salama, Georgia Beasley, David Gooden, Jennifer Y. Zhang
Format: Article
Language:English
Published: Elsevier 2021-09-01
Series:JID Innovations
Online Access:http://www.sciencedirect.com/science/article/pii/S2667026721000448