IL-33 promotes innate lymphoid cell-dependent IFN-γ production required for innate immunity to Toxoplasma gondii

IL-33 promotes innate lymphoid cell-dependent IFN-γ production required for innate immunity to Toxoplasma gondii

IL-33 is an alarmin required for resistance to the parasite Toxoplasma gondii, but its role in innate resistance to this organism is unclear. Infection with T. gondii promotes increased stromal cell expression of IL-33, and levels of parasite replication correlate with release of IL-33 in affected t...

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Bibliographic Details
Main Authors: Joseph T Clark, David A Christian, Jodi A Gullicksrud, Joseph A Perry, Jeongho Park, Maxime Jacquet, James C Tarrant, Enrico Radaelli, Jonathan Silver, Christopher A Hunter
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2021-04-01
Series:eLife
Subjects:
Toxoplasma gondii
IL-33
IL-1 family
innate lymphoid cells
Online Access:https://elifesciences.org/articles/65614

Internet

https://elifesciences.org/articles/65614

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