Reorganization of the nuclear architecture in the Drosophila melanogaster Lamin B mutant lacking the CaaX box

Lamins interact with the nuclear membrane and chromatin but the precise players and mechanisms of these interactions are unknown. Here, we tested whether the removal of the CaaX motif from Lamin B disrupts its attachment to the nuclear membrane and affects chromatin distribution. We used Drosophila...

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Bibliographic Details
Main Authors: Semen M. Bondarenko, Igor V. Sharakhov
Format: Article
Language:English
Published: Taylor & Francis Group 2020-01-01
Series:Nucleus
Subjects:
dm0
Online Access:http://dx.doi.org/10.1080/19491034.2020.1819704