Human keratinocytes are vanilloid resistant.

Human keratinocytes are vanilloid resistant.

BACKGROUND: Use of capsaicin or resiniferatoxin (RTX) as analgesics is an attractive therapeutic option. RTX opens the cation channel inflammatory pain/vanilloid receptor type 1 (TRPV1) permanently and selectively removes nociceptive neurons by Ca(2+)-cytotoxicity. Paradoxically, not only nociceptor...

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Main Authors: László Pecze, Kornélia Szabó, Márta Széll, Katalin Jósvay, Krisztián Kaszás, Erzsébet Kúsz, Tamás Letoha, János Prorok, István Koncz, András Tóth, Lajos Kemény, Csaba Vizler, Zoltán Oláh
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2008-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2566593?pdf=render

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http://europepmc.org/articles/PMC2566593?pdf=render

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