G-CSF prevents the progression of structural disintegration of white matter tracts in amyotrophic lateral sclerosis: a pilot trial.

G-CSF prevents the progression of structural disintegration of white matter tracts in amyotrophic lateral sclerosis: a pilot trial.

<h4>Background</h4>The hematopoietic protein Granulocyte-colony stimulating factor (G-CSF) has neuroprotective and -regenerative properties. The G-CSF receptor is expressed by motoneurons, and G-CSF protects cultured motoneuronal cells from apoptosis. It therefore appears as an attractiv...

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Main Authors: Thomas Duning, Hagen Schiffbauer, Tobias Warnecke, Siawoosh Mohammadi, Agnes Floel, Katja Kolpatzik, Harald Kugel, Armin Schneider, Stefan Knecht, Michael Deppe, Wolf Rüdiger Schäbitz
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-03-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/21423758/?tool=EBI

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https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/21423758/?tool=EBI

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