Metal-dependent regulation of ATP7A and ATP7B in fibroblast cultures

Deficiency of one of the copper transporters ATP7A and ATP7B leads to the rare X-linked disorder Menkes Disease (MD) or the rare autosomal disorder Wilson disease (WD), respectively. In order to investigate whether the ATP7A and the ATP7B genes may be transcriptionally regulated, we measured the exp...

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Bibliographic Details
Main Authors: Lenartowicz Malgorzata, Torben Moos, Mateusz Ogorek, Thomas G Jensen, Lisbeth Birk Møller
Format: Article
Language:English
Published: Frontiers Media S.A. 2016-08-01
Series:Frontiers in Molecular Neuroscience
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fnmol.2016.00068/full