Impact of AMP-Activated Protein Kinase α1 Deficiency on Tissue Injury following Unilateral Ureteral Obstruction.

Impact of AMP-Activated Protein Kinase α1 Deficiency on Tissue Injury following Unilateral Ureteral Obstruction.

AMP-activated protein kinase (Ampk) is a sensor of the cellular energy status and a powerful regulator of metabolism. Activation of Ampk was previously shown to participate in monocyte-to-fibroblast transition and matrix protein production in renal tissue. Thus, the present study explored whether th...

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Bibliographic Details
Main Authors: Sobuj Mia, Giuseppina Federico, Martina Feger, Tatsiana Pakladok, Adrian Meissner, Jakob Voelkl, Hermann-Josef Groene, Ioana Alesutan, Florian Lang
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4540418?pdf=render

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http://europepmc.org/articles/PMC4540418?pdf=render

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