Lack of AKT in adipocytes causes severe lipodystrophy

Objective: Adipose depot mass is tightly regulated to maintain energy homeostasis. AKT is a critical kinase in the insulin-signaling cascade that is required for the process of adipogenesis in vitro. However, the role of AKT in the maintenance and/or function of mature adipocytes in vivo had not bee...

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Bibliographic Details
Main Authors: Abigail L. Shearin, Bobby R. Monks, Patrick Seale, Morris J. Birnbaum
Format: Article
Language:English
Published: Elsevier 2016-07-01
Series:Molecular Metabolism
Online Access:http://www.sciencedirect.com/science/article/pii/S2212877816300382