MADD knock-down enhances doxorubicin and TRAIL induced apoptosis in breast cancer cells.

MADD knock-down enhances doxorubicin and TRAIL induced apoptosis in breast cancer cells.

The Map kinase Activating Death Domain containing protein (MADD) isoform of the IG20 gene is over-expressed in different types of cancer tissues and cell lines and it functions as a negative regulator of apoptosis. Therefore, we speculated that MADD might be over-expressed in human breast cancer tis...

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Bibliographic Details
Main Authors: Andrea Turner, Liang-Cheng Li, Tania Pilli, Lixia Qian, Elizabeth Louise Wiley, Suman Setty, Konstantin Christov, Lakshmy Ganesh, Ajay V Maker, Peifeng Li, Prasad Kanteti, Tapas K Das Gupta, Bellur S Prabhakar
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3574069?pdf=render

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http://europepmc.org/articles/PMC3574069?pdf=render

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