p62: Friend or Foe? Evidences for <i>OncoJanus</i> and <i>NeuroJanus</i> Roles

p62 is a versatile protein involved in the delicate balance between cell death and survival, which is fundamental for cell fate decision in the context of both cancer and neurodegenerative diseases. As an autophagy adaptor, p62 recognizes polyubiquitin chains and interacts with LC3, thereby targetin...

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Bibliographic Details
Main Authors: Sonia Emanuele, Marianna Lauricella, Antonella D’Anneo, Daniela Carlisi, Anna De Blasio, Diana Di Liberto, Michela Giuliano
Format: Article
Language:English
Published: MDPI AG 2020-07-01
Series:International Journal of Molecular Sciences
Subjects:
p62
Online Access:https://www.mdpi.com/1422-0067/21/14/5029