Repurposing of Biologic and Targeted Synthetic Anti-Rheumatic Drugs in COVID-19 and Hyper-Inflammation: A Comprehensive Review of Available and Emerging Evidence at the Peak of the Pandemic

Repurposing of Biologic and Targeted Synthetic Anti-Rheumatic Drugs in COVID-19 and Hyper-Inflammation: A Comprehensive Review of Available and Emerging Evidence at the Peak of the Pandemic

Coronavirus disease 2019 (COVID-19) is a condition caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Severe cases of COVID-19 result in acute respiratory distress syndrome and death. A detrimental, hyper-inflammatory immune response with excess release of cytokines is the m...

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Bibliographic Details
Main Authors: Giulio Cavalli, Nicola Farina, Corrado Campochiaro, Giacomo De Luca, Emanuel Della-Torre, Alessandro Tomelleri, Lorenzo Dagna
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-12-01
Series:Frontiers in Pharmacology
Subjects:
Coronavirus disease 2019
severe acute respiratory syndrome coronavirus 2
disease modifying anti-rheumatic drug
DMARDs (biologic)
cytokine
immunesuppressants
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2020.598308/full

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https://www.frontiersin.org/articles/10.3389/fphar.2020.598308/full

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