Short-term withdrawal of mitogens prior to plating increases neuronal differentiation of human neural precursor cells.

Short-term withdrawal of mitogens prior to plating increases neuronal differentiation of human neural precursor cells.

BACKGROUND: Human neural precursor cells (hNPC) are candidates for neural transplantation in a wide range of neurological disorders. Recently, much work has been done to determine how the environment for NPC culture in vitro may alter their plasticity. Epidermal growth factor (EGF) and fibroblast gr...

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Bibliographic Details
Main Authors: Telma Tiemi Schwindt, Fabiana Louise Motta, Gabriela Filoso Barnabé, Cristina Gonçalves Massant, Alessander de Oliveira Guimarães, Maria Elisa Calcagnotto, Fabio Silva Conceição, João Bosco Pesquero, Stevens Rehen, Luiz E Mello
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2009-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2646132?pdf=render

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http://europepmc.org/articles/PMC2646132?pdf=render

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