Molecular assembly and biosynthesis of acetylcholinesterase in brain and muscle: The roles of t-peptide, FHB domain and N-linked glycosylation

Molecular assembly and biosynthesis of acetylcholinesterase in brain and muscle: The roles of t-peptide, FHB domain and N-linked glycosylation

Acetylcholinesterase (AChE) is responsible for the hydrolysis of the neurotransmitter, acetylcholine, in the nervous system. The functional localization and oligomerization of AChE T variant are depending primarily on the association of their anchoring partners, either collagen tail (ColQ) or prolin...

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Bibliographic Details
Main Authors: Vicky P. Chen, Wilson K.W. Luk, Wallace K.B. Chan, K. Wing eLeung, Ava J.Y. Guo, Gallant K.L. Chan, Sherry L. Xu, Roy C.Y. Choi, Karl W.K. Tsim
Format: Article
Language:English
Published: Frontiers Media S.A. 2011-10-01
Series:Frontiers in Molecular Neuroscience
Subjects:
Acetylcholinesterase
Butyrylcholinesterase
Glycosylation
Membrane trafficking
Assembly
Online Access:http://journal.frontiersin.org/Journal/10.3389/fnmol.2011.00036/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fnmol.2011.00036/full

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