Indomethacin solubility estimation in 1,4-dioxane + water mixtures by the extended hildebrand solubility approach

Extended Hildebrand Solubility Approach (EHSA) was successfully applied to evaluate the solubility of Indomethacin in 1,4-dioxane + water mixtures at 298.15 K. An acceptable correlation-performance of EHSA was found by using a regular polynomial model in order four of the W interaction parameter vs....

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Bibliographic Details
Main Authors: Miller A Ruidiaz, Daniel R Delgado, Fleming Martínez
Format: Article
Language:English
Published: Sociedade Brasileira de Química 2011-09-01
Series:Química Nova
Subjects:
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-40422011000900016&lng=en&tlng=en