RPN2 Gene Confers Osteosarcoma Cell Malignant Phenotypes and Determines Clinical Prognosis

RPN2 Gene Confers Osteosarcoma Cell Malignant Phenotypes and Determines Clinical Prognosis

Drug resistance and metastasis are lethal characteristics of tumors. We previously demonstrated that silencing of ribophorin II (RPN2), which is part of the N-oligosaccharyl transferase complex, efficiently induced apoptosis and reduced resistance to docetaxel in human breast cancer cells. Here, we...

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Bibliographic Details
Main Authors: Tomohiro Fujiwara, Ryou-u Takahashi, Nobuyoshi Kosaka, Yutaka Nezu, Akira Kawai, Toshifumi Ozaki, Takahiro Ochiya
Format: Article
Language:English
Published: Elsevier 2014-01-01
Series:Molecular Therapy: Nucleic Acids
Subjects:
drug response
metastasis
osteosarcoma
ribophorin II (RPN2)
RNA interference
Online Access:http://www.sciencedirect.com/science/article/pii/S2162253116303298

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http://www.sciencedirect.com/science/article/pii/S2162253116303298

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