Successful treatment of refractory hyperferritinemic syndromes with canakinumab: a report of two cases

Successful treatment of refractory hyperferritinemic syndromes with canakinumab: a report of two cases

Abstract Background Hyperferritinemic syndromes are systemic inflammatory disorders characterized by a dysfunctional immune response, which leads to excessive activation of the monocyte-macrophage system with hypercytokinemia and may pursue a rapidly fatal course. Case presentation We describe two p...

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Bibliographic Details
Main Authors: Riccardo Papa, Valentina Natoli, Roberta Caorsi, Francesca Minoia, Marco Gattorno, Angelo Ravelli
Format: Article
Language:English
Published: BMC 2020-07-01
Series:Pediatric Rheumatology Online Journal
Subjects:
Hyperferritinemic syndrome
Macrophage activation syndrome
Hemophagocytic lymphohistiocytosis
Hyperferritinemia
Anakinra
Canakinumab
Online Access:http://link.springer.com/article/10.1186/s12969-020-00450-9

Internet

http://link.springer.com/article/10.1186/s12969-020-00450-9

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