Next-generation sequence assembly: four stages of data processing and computational challenges.

Decoding DNA symbols using next-generation sequencers was a major breakthrough in genomic research. Despite the many advantages of next-generation sequencers, e.g., the high-throughput sequencing rate and relatively low cost of sequencing, the assembly of the reads produced by these sequencers still...

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Bibliographic Details
Main Authors: Sara El-Metwally, Taher Hamza, Magdi Zakaria, Mohamed Helmy
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS Computational Biology
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/24348224/?tool=EBI