Emerging Roles of Liquid–Liquid Phase Separation in Cancer: From Protein Aggregation to Immune-Associated Signaling

Emerging Roles of Liquid–Liquid Phase Separation in Cancer: From Protein Aggregation to Immune-Associated Signaling

Liquid–liquid Phase Separation (LLPS) of proteins and nucleic acids has emerged as a new paradigm in the study of cellular activities. It drives the formation of liquid-like condensates containing biomolecules in the absence of membrane structures in living cells. In addition, typical membrane-less...

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Bibliographic Details
Main Authors: Jiahua Lu, Junjie Qian, Zhentian Xu, Shengyong Yin, Lin Zhou, Shusen Zheng, Wu Zhang
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-06-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
liquid–liquid phase separation
biomolecular condensate
cancer mechanism
protein aggregation
signaling transduction
genome stability
Online Access:https://www.frontiersin.org/articles/10.3389/fcell.2021.631486/full

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https://www.frontiersin.org/articles/10.3389/fcell.2021.631486/full

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