Haplotype analysis of BRCA1 intragenic markers in Iranian patients with familial breast and ovarian cancer

Background: Breast cancer is the most common malignancy in women. Breast Cancer Type 1 Susceptibility gene (BRCA1) is a tumor suppressor gene, involved in DNA damage repair and in 81% of the breast-ovarian cancer families were due to BRCA1. In some clinically investigated genes, the intragenic marke...

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Bibliographic Details
Main Authors: Seyed Mohsen Miresmaeili, Dor Mohammad Kordi Tamandani, Seyed Mehdi Kalantar, Seyed Mohammad Moshtaghioun
Format: Article
Language:English
Published: Shahid Sadoughi University of Medical Science, Yazd, Iran 2016-04-01
Series:Iranian Journal of Reproductive Medicine
Online Access:http://www.ssu.ac.ir/ijrm/index.php/ijrm/article/view/1907/970