The sensitivity of massively parallel sequencing for detecting candidate infectious agents associated with human tissue.

The sensitivity of massively parallel sequencing for detecting candidate infectious agents associated with human tissue.

Massively parallel sequencing technology now provides the opportunity to sample the transcriptome of a given tissue comprehensively. Transcripts at only a few copies per cell are readily detectable, allowing the discovery of low abundance viral and bacterial transcripts in human tissue samples. Here...

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Bibliographic Details
Main Authors: Richard A Moore, René L Warren, J Douglas Freeman, Julia A Gustavsen, Caroline Chénard, Jan M Friedman, Curtis A Suttle, Yongjun Zhao, Robert A Holt
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3094400?pdf=render

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http://europepmc.org/articles/PMC3094400?pdf=render

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