Systematic pathway enrichment analysis of a genome-wide association study on breast cancer survival reveals an influence of genes involved in cell adhesion and calcium signaling on the patients' clinical outcome.

Systematic pathway enrichment analysis of a genome-wide association study on breast cancer survival reveals an influence of genes involved in cell adhesion and calcium signaling on the patients' clinical outcome.

Genome-wide association studies (GWASs) may help to understand the effects of genetic polymorphisms on breast cancer (BC) progression and survival. However, they give only a focused view, which cannot capture the tremendous complexity of this disease. Therefore, we investigated data from a previousl...

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Bibliographic Details
Main Authors: Andrea Woltmann, Bowang Chen, Jesús Lascorz, Robert Johansson, Jorunn E Eyfjörd, Ute Hamann, Jonas Manjer, Kerstin Enquist-Olsson, Roger Henriksson, Stefan Herms, Per Hoffmann, Kari Hemminki, Per Lenner, Asta Försti
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4041745?pdf=render

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http://europepmc.org/articles/PMC4041745?pdf=render

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