A three-dimensional engineered artery model for in vitro atherosclerosis research.

The pathogenesis of atherosclerosis involves dysfunctions of vascular endothelial cells and smooth muscle cells as well as blood borne inflammatory cells such as monocyte-derived macrophages. In vitro experiments towards a better understanding of these dysfunctions are typically performed in two-dim...

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Bibliographic Details
Main Authors: Jérôme Robert, Benedikt Weber, Laura Frese, Maximilian Y Emmert, Dörthe Schmidt, Arnold von Eckardstein, Lucia Rohrer, Simon P Hoerstrup
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/24244566/pdf/?tool=EBI