Molecular dynamics simulations of the interaction of wild type and mutant human CYP2J2 with polyunsaturated fatty acids

Molecular dynamics simulations of the interaction of wild type and mutant human CYP2J2 with polyunsaturated fatty acids

Abstract Objectives The data presented here is part of a study that was aimed at characterizing the molecular mechanisms of polyunsaturated fatty acid metabolism by CYP2J2, the main cytochrome P450 enzyme active in the human cardiovasculature. This part comprises the molecular dynamics simulations o...

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Bibliographic Details
Main Authors: K. K. Abelak, D. Bishop-Bailey, I. Nobeli
Format: Article
Language:English
Published: BMC 2019-11-01
Series:BMC Research Notes
Subjects:
CYP2J2
Cytochrome P450
Polyunsaturated fatty acids
Molecular dynamics
Homology model
Docking
Online Access:http://link.springer.com/article/10.1186/s13104-019-4797-8

Internet

http://link.springer.com/article/10.1186/s13104-019-4797-8

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