Nicotinic cholinergic system and COVID-19: In silico evaluation of nicotinic acetylcholine receptor agonists as potential therapeutic interventions

Nicotinic cholinergic system and COVID-19: In silico evaluation of nicotinic acetylcholine receptor agonists as potential therapeutic interventions

SARS-CoV-2 infection was announced as a pandemic in March 2020. Since then, several scientists have focused on the low prevalence of smokers among hospitalized COVID-19 patients. These findings led to our hypothesis that the Nicotinic Cholinergic System (NCS) plays a crucial role in the manifestatio...

Full description

Bibliographic Details
Main Authors: Nikolaos Alexandris, George Lagoumintzis, Christos T. Chasapis, Demetres D. Leonidas, Georgios E. Papadopoulos, Socrates J. Tzartos, Aristidis Tsatsakis, Elias Eliopoulos, Konstantinos Poulas, Konstantinos Farsalinos
Format: Article
Language:English
Published: Elsevier 2021-01-01
Series:Toxicology Reports
Subjects:
Cholinergic agonists
COVID-19
Nicotinic acetylcholine receptors
SARS-CoV-2
Spike glycoprotein
Online Access:http://www.sciencedirect.com/science/article/pii/S2214750020304583

Internet

http://www.sciencedirect.com/science/article/pii/S2214750020304583

Similar Items