Metal-Regulatory Transcription Factor-1 Targeted by miR-148a-3p Is Implicated in Human Hepatocellular Carcinoma Progression

Metal-Regulatory Transcription Factor-1 Targeted by miR-148a-3p Is Implicated in Human Hepatocellular Carcinoma Progression

Metal-regulatory transcription factor-1 (MTF-1) is of importance in maintaining metal homeostasis. Copper exposure considerably stimulates the proliferation of hepatocellular carcinoma (HCC) cells with enhanced MTF-1 expression. However, the underlying molecular mechanisms have not been completely e...

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Bibliographic Details
Main Authors: Zhuozhen Lyu, Mingyu Yang, Tan Yang, Mingze Ma, Zhen Yang
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-09-01
Series:Frontiers in Oncology
Subjects:
hepatocellular carcinoma
copper
MTF-1
APE/Ref-1
miR-148a-3p
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2021.700649/full

Internet

https://www.frontiersin.org/articles/10.3389/fonc.2021.700649/full

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