Viral inhibition of the transporter associated with antigen processing (TAP): a striking example of functional convergent evolution.

Herpesviruses are large DNA viruses that are highly abundant within their host populations. Even in the presence of a healthy immune system, these viruses manage to cause lifelong infections. This persistence is partially mediated by the virus entering latency, a phase of infection characterized by...

Full description

Bibliographic Details
Main Authors: Marieke C Verweij, Daniëlle Horst, Bryan D Griffin, Rutger D Luteijn, Andrew J Davison, Maaike E Ressing, Emmanuel J H J Wiertz
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-04-01
Series:PLoS Pathogens
Online Access:http://europepmc.org/articles/PMC4399834?pdf=render