The Role of HSP90α in Methamphetamine/Hyperthermia-Induced Necroptosis in Rat Striatal Neurons

The Role of HSP90α in Methamphetamine/Hyperthermia-Induced Necroptosis in Rat Striatal Neurons

Methamphetamine (METH) is one of the most widely abused synthetic drugs in the world. The users generally present hyperthermia (HT) and psychiatric symptoms. However, the mechanisms involved in METH/HT-induced neurotoxicity remain elusive. Here, we investigated the role of heat shock protein 90 alph...

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Bibliographic Details
Main Authors: Lv-shuang Liao, Shuang Lu, Wei-tao Yan, Shu-chao Wang, Li-min Guo, Yan-di Yang, Kai Huang, Xi-min Hu, Qi Zhang, Jie Yan, Kun Xiong
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-07-01
Series:Frontiers in Pharmacology
Subjects:
methamphetamine
hyperthermia
heat shock protein 90 alpha
necroptosis
receptor-interacting protein 3
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2021.716394/full

Internet

https://www.frontiersin.org/articles/10.3389/fphar.2021.716394/full

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