Epitope mapping of HIV-specific CD8+ T cells in a cohort dominated by clade A1 infection.

CD8+ T cell responses are often detected at large magnitudes in HIV-infected subjects, and eliciting these responses is the central aim of many HIV-1 vaccine strategies. Population differences in CD8+ T cell epitope specificity will need to be understood if vaccines are to be effective in multiple g...

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Bibliographic Details
Main Authors: Lyle R McKinnon, Xiaojuan Mao, Joshua Kimani, Charles Wachihi, Christina Semeniuk, Mark Mendoza, Binhua Liang, Ma Luo, Keith R Fowke, Francis A Plummer, T Blake Ball
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2009-09-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2735720?pdf=render