Functional crosstalk between type I and II interferon through the regulated expression of STAT1.

Functional crosstalk between type I and II interferon through the regulated expression of STAT1.

Autocrine priming of cells by small quantities of constitutively produced type I interferon (IFN) is a well-known phenomenon. In the absence of type I IFN priming, cells display attenuated responses to other cytokines, such as anti-viral protection in response to IFNgamma. This phenomenon was propos...

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Bibliographic Details
Main Authors: Daniel J Gough, Nicole L Messina, Linda Hii, Jodee A Gould, Kanaga Sabapathy, Ashley P S Robertson, Joseph A Trapani, David E Levy, Paul J Hertzog, Christopher J P Clarke, Ricky W Johnstone
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-04-01
Series:PLoS Biology
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/20436908/pdf/?tool=EBI

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https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/20436908/pdf/?tool=EBI

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