Heat shock proteins in tumor immunity: mediators of antigen presentation and inflammation?

Heat shock protein (HSP)-based anticancer vaccines have undergone successful preclinical testing and are now undergoing clinical trial. Questions still however remain regarding the immunological properties of HSPs. It is now accepted that HSPs participate in tumor immunity by chaperoning tumor antig...

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Bibliographic Details
Main Authors: Stuart Keith Calderwood, Ayesha eMurshid, Jianlin eGong
Format: Article
Language:English
Published: Frontiers Media S.A. 2012-04-01
Series:Frontiers in Immunology
Subjects:
TLR
Online Access:http://journal.frontiersin.org/Journal/10.3389/fimmu.2012.00075/full