Multi-scale imaging and analysis identify pan-embryo cell dynamics of germlayer formation in zebrafish

The precise cell dynamics of early development have not yet been visualized. Here, the authors use custom 4-lens light sheet microscopy to image and analyze the dynamics of all three fluorescently labeled germlayers, yielding a comprehensive, pan-embryo description of early zebrafish gastrulation.

Bibliographic Details
Main Authors: Gopi Shah, Konstantin Thierbach, Benjamin Schmid, Johannes Waschke, Anna Reade, Mario Hlawitschka, Ingo Roeder, Nico Scherf, Jan Huisken
Format: Article
Language:English
Published: Nature Publishing Group 2019-12-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-019-13625-0