Closed-Loop Deep Brain Stimulation Effects on Parkinsonian Motor Symptoms in a Non-Human Primate – Is Beta Enough?

Closed-Loop Deep Brain Stimulation Effects on Parkinsonian Motor Symptoms in a Non-Human Primate – Is Beta Enough?

Background: Incorporating feedback controls based on real-time measures of pathological brain activity may improve deep brain stimulation (DBS) approaches for the treatment of Parkinson's disease (PD). Excessive beta oscillations in subthalamic nucleus (STN) local field potentials (LFP) have be...

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Bibliographic Details
Main Authors: Luke A. Johnson, Shane D. Nebeck, Abirami Muralidharan, Matthew D. Johnson, Kenneth B. Baker, Jerrold L. Vitek
Format: Article
Language:English
Published: Elsevier 2016-11-01
Series:Brain Stimulation
Subjects:
Deep brain stimulation
Parkinson's disease
Subthalamic nucleus
Local field potentials
Closed-loop
Online Access:http://www.sciencedirect.com/science/article/pii/S1935861X16301887

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http://www.sciencedirect.com/science/article/pii/S1935861X16301887

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