Systemic administration of antiretrovirals prior to exposure prevents rectal and intravenous HIV-1 transmission in humanized BLT mice.

Systemic administration of antiretrovirals prior to exposure prevents rectal and intravenous HIV-1 transmission in humanized BLT mice.

Successful antiretroviral pre-exposure prophylaxis (PrEP) for mucosal and intravenous HIV-1 transmission could reduce new infections among targeted high-risk populations including discordant couples, injection drug users, high-risk women and men who have sex with men. Targeted antiretroviral PrEP co...

Full description

Bibliographic Details
Main Authors: Paul W Denton, John F Krisko, Daniel A Powell, Melissa Mathias, Youn Tae Kwak, Francisco Martinez-Torres, Wei Zou, Deborah A Payne, Jacob D Estes, J Victor Garcia
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2809117?pdf=render

Internet

http://europepmc.org/articles/PMC2809117?pdf=render

Similar Items