Single Particle Tracking Reveals that EGFR Signaling Activity Is Amplified in Clathrin-Coated Pits.

Single Particle Tracking Reveals that EGFR Signaling Activity Is Amplified in Clathrin-Coated Pits.

Signaling from the epidermal growth factor receptor (EGFR) via phosphorylation on its C-terminal tyrosine residues requires self-association, which depends on the diffusional properties of the receptor and its density in the plasma membrane. Dimerization is a key event for EGFR activation, but the r...

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Bibliographic Details
Main Authors: Jenny Ibach, Yvonne Radon, Márton Gelléri, Michael H Sonntag, Luc Brunsveld, Philippe I H Bastiaens, Peter J Verveer
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4648588?pdf=render

Internet

http://europepmc.org/articles/PMC4648588?pdf=render

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