Trained Immunity-Based Vaccine in B Cell Hematological Malignancies With Recurrent Infections: A New Therapeutic Approach

Trained Immunity-Based Vaccine in B Cell Hematological Malignancies With Recurrent Infections: A New Therapeutic Approach

Infectious complications are a major cause of morbidity and mortality in B-cell hematological malignancies (HM). Prophylaxis for recurrent infections in HM patients with antibody deficiency consists of first-line antibiotics and when unsuccessful, gammaglobulin replacement therapy (IgRT). Recent kno...

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Bibliographic Details
Main Authors: Juliana Ochoa-Grullón, Celina Benavente Cuesta, Ataúlfo González Fernández, Gustavo Cordero Torres, Cristina Pérez López, Ascensión Peña Cortijo, Laura Conejero Hall, Marta Mateo Morales, Antonia Rodríguez de la Peña, Carmen M. Díez-Rivero, Edgard Rodríguez de Frías, Kissy Guevara-Hoyer, Miguel Fernández-Arquero, Silvia Sánchez-Ramón
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-02-01
Series:Frontiers in Immunology
Subjects:
hematological malignancies
IgA
recurrent respiratory tract infections
trained immunity-based vaccines
MV130
prophylaxis
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2020.611566/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2020.611566/full

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