Bile Acid Signal Molecules Associate Temporally with Respiratory Inflammation and Microbiome Signatures in Clinically Stable Cystic Fibrosis Patients

Bile Acid Signal Molecules Associate Temporally with Respiratory Inflammation and Microbiome Signatures in Clinically Stable Cystic Fibrosis Patients

Cystic fibrosis (CF) is a congenital disorder resulting in a multisystemic impairment in ion homeostasis. The subsequent alteration of electrochemical gradients severely compromises the function of the airway epithelia. These functional changes are accompanied by recurrent cycles of inflammation–inf...

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Bibliographic Details
Main Authors: Stephanie Flynn, F. Jerry Reen, Jose A. Caparrós-Martín, David F. Woods, Jörg Peplies, Sarath C. Ranganathan, Stephen M. Stick, Fergal O'Gara
Format: Article
Language:English
Published: MDPI AG 2020-11-01
Series:Microorganisms
Subjects:
cystic fibrosis
bile acids
lung microbiota
inflammation
gut–lung axis
Online Access:https://www.mdpi.com/2076-2607/8/11/1741

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https://www.mdpi.com/2076-2607/8/11/1741

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