Glycyrrhizin Acid and Glycyrrhetinic Acid Modified Polyethyleneimine for Targeted DNA Delivery to Hepatocellular Carcinoma

Glycyrrhizin Acid and Glycyrrhetinic Acid Modified Polyethyleneimine for Targeted DNA Delivery to Hepatocellular Carcinoma

In the last 2−3 decades, gene therapy represented a promising option for hepatocellular carcinoma (HCC) treatment. However, the design of safe and efficient gene delivery systems is still one of the major challenges that require solutions. In this study, we demonstrate a versatile method f...

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Bibliographic Details
Main Authors: Mingzhuo Cao, Yong Gao, Mengling Zhan, Nasha Qiu, Ying Piao, Zhuxian Zhou, Youqing Shen
Format: Article
Language:English
Published: MDPI AG 2019-10-01
Series:International Journal of Molecular Sciences
Subjects:
gene therapy
glycyrrhizin acid
glycyrrhetinic acid
hepatic tumor targeting
caveolae- and clathrin-independent pathway
hepg2 intraperitoneal tumor model
Online Access:https://www.mdpi.com/1422-0067/20/20/5074

Internet

https://www.mdpi.com/1422-0067/20/20/5074

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