Challenges of culturing human norovirus in three-dimensional organoid intestinal cell culture models.

Human noroviruses are the most common cause of acute gastroenteritis worldwide. Recently, cell culture systems have been described using either human embryonic intestinal epithelial cells (Int-407) or human epithelial colorectal adenocarcinoma cells (Caco-2) growing on collagen-I porous micro carrie...

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Bibliographic Details
Main Authors: Efstathia Papafragkou, Joanne Hewitt, Geun Woo Park, Gail Greening, Jan Vinjé
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3670855?pdf=render