Genetic basis of growth adaptation of Escherichia coli after deletion of pgi, a major metabolic gene.
Bacterial survival requires adaptation to different environmental perturbations such as exposure to antibiotics, changes in temperature or oxygen levels, DNA damage, and alternative nutrient sources. During adaptation, bacteria often develop beneficial mutations that confer increased fitness in the...
| Main Authors: | , , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Public Library of Science (PLoS)
2010-11-01
|
| Series: | PLoS Genetics |
| Online Access: | http://europepmc.org/articles/PMC2973815?pdf=render |