Differential Viral-Host Immune Interactions Associated with Oseltamivir-Resistant H275Y and Wild-Type H1N1 A(pdm09) Influenza Virus Pathogenicity

Differential Viral-Host Immune Interactions Associated with Oseltamivir-Resistant H275Y and Wild-Type H1N1 A(pdm09) Influenza Virus Pathogenicity

Oseltamivir is a common therapy against influenza A virus (IAV) infections. The acquisition of oseltamivir resistance (OR) mutations, such as H275Y, hampers viral fitness. However, OR H1N1 viruses have demonstrated the ability to spread throughout different populations. The objective of this work wa...

Full description

Bibliographic Details
Main Authors: Beatriz Vidaña, Pamela Martínez-Orellana, Jaime M. Martorell, Massimiliano Baratelli, Jorge Martínez, Lourdes Migura-Garcia, Lorena Córdoba, Mónica Pérez, Inmaculada Casas, Francisco Pozo, Lorenzo Fraile, Natàlia Majó, María Montoya
Format: Article
Language:English
Published: MDPI AG 2020-07-01
Series:Viruses
Subjects:
influenza
immunopathology
pneumonia
pH1N1
resistance
oseltamivir
Online Access:https://www.mdpi.com/1999-4915/12/8/794

Internet

https://www.mdpi.com/1999-4915/12/8/794

Similar Items