Optical coherence tomography-based contact indentation for diaphragm mechanics in a mouse model of transforming growth factor alpha induced lung disease

Abstract This study tested the utility of optical coherence tomography (OCT)-based indentation to assess mechanical properties of respiratory tissues in disease. Using OCT-based indentation, the elastic modulus of mouse diaphragm was measured from changes in diaphragm thickness in response to an app...

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Bibliographic Details
Main Authors: Kimberley C. W. Wang, Chrissie J. Astell, Philip Wijesinghe, Alexander N. Larcombe, Gavin J. Pinniger, Graeme R. Zosky, Brendan F. Kennedy, Luke J. Berry, David D. Sampson, Alan L. James, Timothy D. Le Cras, Peter B. Noble
Format: Article
Language:English
Published: Nature Publishing Group 2017-05-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-017-01431-x