Optical coherence tomography-based contact indentation for diaphragm mechanics in a mouse model of transforming growth factor alpha induced lung disease
Abstract This study tested the utility of optical coherence tomography (OCT)-based indentation to assess mechanical properties of respiratory tissues in disease. Using OCT-based indentation, the elastic modulus of mouse diaphragm was measured from changes in diaphragm thickness in response to an app...
Main Authors: | Kimberley C. W. Wang, Chrissie J. Astell, Philip Wijesinghe, Alexander N. Larcombe, Gavin J. Pinniger, Graeme R. Zosky, Brendan F. Kennedy, Luke J. Berry, David D. Sampson, Alan L. James, Timothy D. Le Cras, Peter B. Noble |
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Format: | Article |
Language: | English |
Published: |
Nature Publishing Group
2017-05-01
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Series: | Scientific Reports |
Online Access: | https://doi.org/10.1038/s41598-017-01431-x |
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